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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41481cc118b4278ce0e3baa79bc9cbc3431d3271008318d5333ce3bc71daeaa1' 
  AND token = 'T/vhWypZX7+FP2REtHfNDsgbHkjeDV3kRD49KNqz6T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}