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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d022401e3b90dbe16092691b5a8f2754ad1cfc2c1cbe9498061e9fa8c1eb282' 
  AND token = 'm0OV0dOTGJHBVWBZA9Kkgrjezt4U0WJsGxUHr61BG+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}