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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaa16b30bba85d1435eef8b2c2dd32a3be576b739780e36966abc5fdc6ec8c97' 
  AND token = 'UhwC6/NGVbMZcgxR7C0UsM4zZOjp6j0OLvDcyRgE6Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}