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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f4a29bbe6fd8a16ce54e9647c977b6e77bb46f52ca9f10cb84ea5ecd61eced' 
  AND token = 'itXzc58H342DhVUGB9gGca6ddg7mxhHWargd9jXraRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}