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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45d9a4cdd4162e4f0741d41b328e539ab67176fd56c155bee684f3e86bd9bd3' 
  AND token = 'k4U5PCREWl5zcmtJfkSYtp0aQmztX+oEw0WmgvcmbDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}