SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd435683cf0c9be45cb6dac8d9769a53c0586ffea4bdf41f7b759ce30ef90fc7c' 
  AND token = 'Ccb1L0c6kbP5tfFZNW9RfaUYc+buj5GvOzD7D2QWgjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}