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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9297e7d84c82dfcaf41cd49e265008f8f9e9d7096064f72fc9000911848da866' 
  AND token = 'KU+bAdL0Bzssl0s9TWWhy1MjeIMsF9HIgbn6xe2/xbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}