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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3307b7e7f72ee6da077f49f15d2604b0ce96ee082c4c39ff3d0279669535c7d2' 
  AND token = 'v/ZTQPPR6NRzf+fNPO0Ohd2hGbD/jLnxjvjllRvNpBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}