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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff1306987f607c95b91ee602f5288d73cfe9ab69865fee3c5298597ad25e5a64' 
  AND token = 'LTgwEZ7TO3FdmxFgRKNkmAlF6BhHBSlAhF9TmTj2WcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}