SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cac1deb35e7f642543df17c76f9ecf7d3f77e423565ff5492472784d478d5f1a' 
  AND token = 'Z7pRirwBTcz2QvznoH6+n9m8bPfH0pvrqwfLZuPrwnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}