SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25cd9af001db53bcf9460583646d3e09ac62d4ba78ab263234188cbd4078872f' 
  AND token = 'TnnIh/uTJGQIsETNhZRw78X9B/wkhPXwUjRFvAjKidU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}