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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '860338e16093bfcb2d5e771fbca437dd10f646473a743c70004a71465d1dc6d8' 
  AND token = 'poMpK47yzZ7yGmUGv5l1wENmS5A5aFiMi+3xjbJiDFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}