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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b3270d78b724162e488b457fbf064e9eb20b71bafb5861f120f38ba31d0318' 
  AND token = 'LpN6bcCIoEUPUxY9OgYDyo2nxBjGnq2h1uUnP/orep0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}