SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403e348f45f6c740e7bcf90aee64a7ddc821a3e2bb95830f081a5b0f66adf1a1' 
  AND token = 'xRVe2phgWN88Gse48jOtIPxl3J/o7Kx9tRaTB2AOfgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}