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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c9d04ffc083faf79ca0101c1cd84fb47c368563ea1da56c4560ea5ff06b42c' 
  AND token = 'M6usLAhJlTtGjcTiTJrVJnV9AqpIxS41R8c/sq8NI3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}