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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2d7e98a24b81bd5a3bf11c9d4ff5eb390d9098e11a6ef61b5b4a16a8b5fa5c' 
  AND token = 'NhkXhSjVcD7mw1ZQTkbLnWw6mtricDF8vC9Vy393F30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}