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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9368d027ccde81bb094a925c46553a395182c6b2c5028eb1a272a4d43f33b012' 
  AND token = 'bOaQzEFZ5zk5KjJH9lKrkyhnCiai6f1s9uWNSujQPoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}