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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f2d5520be0f822083a85a94e4c7aff820b16db2af08ad4c50a7f644add5a81' 
  AND token = 'AXKOOqk1RRzBJ1RsWDQ189toohI3+lErddepakKVdo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}