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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d3bc0f550f9cf2176470bb472d67b1844db0c7bea319fd0f4fd34823c2fe5c' 
  AND token = 'vkyshYmESewj2I5jNPmuVv0W6G1Q0vb4D+RQa88NOhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}