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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4c757f3b6ff06dadf7fb39579329d5a0b4d511fc64fdffe19ca782a5363047' 
  AND token = 'HfTQfZ0Out6Xv+Y8qwf1Y6NS2gyidOdRcN4qBNqjK8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}