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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4535f21485fcd0d0a4a6a3cab86a66b41a7e773a6481b9e1abdb38bde8d0a67f' 
  AND token = '5GCPQiqEXD4rudQ7HK195K+ZCsQMobY+slUnBm2fMpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}