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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91d2ff7339ed00389960c4bc19b06dc9617b66bb37045c47e3653be170c48648' 
  AND token = '7DPNaajZ2nlinTGrVcztohzZrW8VTEQqaoeYFfiH1EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}