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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45af38f76911a32eb06a80237581af7530e7a711ae3f71c95ab2998e3abe564b' 
  AND token = '7C+3qWR3IxPWQuNm23JfJOfcyrJ9zcibW9fsLOPeXhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}