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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c1d564074e80ea283ec3920b562a157cf5101d6bbc6e479dbbe0b53610a1e8' 
  AND token = 'Luc/o9ajcjGG3pGQqc1AbiMYRL//d4/K9p/LpKN9iYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}