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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc01271d12f0892c3e62139f37da0fa1f9da50b6ae86565f6c0ffc66bde33f18' 
  AND token = 'AoSctz/sgOr6IBXrWRJfQJfgKB5vEeWA/SbDkJ+8ggY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}