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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72456e1c98621b81d51928bd7eff167bbe7fc4510af7e60200d9b0979599189a' 
  AND token = 'y/j+6jg7GeWaMXU01vq62iwUzOJGKm0Ck05DBVNrIk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}