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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11324eff0b1a11908f65f46b0b5a24b1f4c1207afc709cd83fb96c5cf0c67a6c' 
  AND token = 'joEpOqH3vXyEq9k2Oxdxal2K1jxA6TfZT0vSC2qqdD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}