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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76648aff5de82b76f048c7cf49e93b439d19c7aa5184bd561953b3638c6bf84a' 
  AND token = 'ZX2m3SpNMc8jh58bHiTDgG2KW7drRm9xeynmemCFNC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}