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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82b3fd4ab6da1ad742f930bf9e4f015b457b0a4a217edc0162e5a9307fb6d716' 
  AND token = 'QtK1o5n+/EL6m3cC3xKshKmCLZZkWKtfD7MHx7qA6ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}