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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819689a0c180aa203ead7a8ea4ab1b560096a8ebb6d2535f43e6b3436ce3e2ea' 
  AND token = 'lXriT36W3Pdt/3UYWPCq5Cj77e0A9DgmHPc3+FRRiHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}