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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5091f84413bbb3da3b37674161c5cfe6a26fe2a81f13a3a2efec9f3ffdfc9d' 
  AND token = 'USPfCrxFTlrM2wXhKnrMTV4ckLtoEp69L9hkqeyHbDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}