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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d99d59788c4451d5857b109a8094cf18b38796235c7bc2e187bee66444a5fb' 
  AND token = 'ntRI9iJKGy1hJyLL3yC64pd4BJe8MLOSURj7jZMRgJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}