SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee2970dbd6bd60e270235fef1dc9e4d2f39cdb244a38f8e16c4ee9f839015e0' 
  AND token = 'TDsStP66NsBo39iCMOuYAmqQJRAN58Pb/AVh3v3YGm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}