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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c3a01f70a2ca837351109ada164751064826a71ee9a791e50a610bfdb7df8d' 
  AND token = 'Z4JSPkuEjmc2upEh6IHwyf/Rk/GQXrnXV/Xhf1oyQVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}