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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26df37b547b5a766fd13731a9f8ddfc886fe880ca405c8da25ce06bcb9a0ae30' 
  AND token = 'nJRg45sVC7+7wkQ8aLw+xocaOnJoXq2l7bvyECmuZjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}