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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888e625c79e78f99af898e21a6e5c8cb56bc7e5e729415fa37e531c1c9f5d242' 
  AND token = 'FLOtOmuuVm+gabRy+oKqpqp8m7zTu6Ax7Ny8yK3MBBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}