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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0eb27260c3d38663361f9099d718eecb4588484a2eaff04b3186f735c3717c' 
  AND token = 'vNeLMfoXA9aoLX5vzy6vm+SyG3PE2RcjGDNdJJ+Iy1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}