SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880fee0251c2dcd02edfa1e09c54964d2895c9b37e9f6df8227af7edc9014de7' 
  AND token = 'qWu2D+7AZbhj23CMmNaxRI+0d8C6U+/KqJj4BsGtXpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}