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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e54d0ec6529d797d3d1958bf1c2f40e5c72a83850db7a9ae84f6732c1a37d7' 
  AND token = 'uXwutXPhdtJ3Os5PXFXVHVmSmcvjbpWm30ZaZgHoh1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}