SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525bdd78d942b9aa3dabf10d4d5367a9f83874fceee6e9a702928ec925022a3e' 
  AND token = '1GKWM72fpiWmeD3LV46KZ/icNvh8lCh1dhVkUIIxJAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}