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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e67e81c4f5249e768174a52146f025b8db7d0344aa92138c6cd1d1d841efb6c' 
  AND token = '8f0ZEL/dXEHK3R6KjSyrUiLoFnGk+si0LjQAhFujg8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}