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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de3e6307d9c3b0f029f9bba42d34d6de43a3cb19b5d6223175593563a24a6c3' 
  AND token = 'OpnDJISe6aYXWv131esxcwa7HR10SEa6B7H9iZrIaQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}