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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20cf1e971a58bffbd15473416fc444fb608fd6b657978d9128c53afda0d60dce' 
  AND token = 'O5Avkb/HKT8vMAkKJkJCp++JCWlFW2Xy7d2dtY1N7gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}