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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec0cc6fe48beec0846d2cc19b4c6abad23eff8c3dc5078a9da584f5d3c83736' 
  AND token = 'hJIUQTTh48CKkMIh3B12uCWoSLU6OlTDuB7QdeEeraI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}