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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00b3ad6e4f2cb9d2584dbc68b5afa84800f2e9d8179d61e2a9522e65e07d393' 
  AND token = 'LojEK1IokjdyEDWitLO69WK1UGGz4w2VRfw4Jiz1hA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}