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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99cdb72a8ff40b2be79d7ebe88a56d3d19ad1a787042e1878ec16f0b6a4c9da6' 
  AND token = 'D6HpRMguMTd8aQe3F/s6uhiH8LrXL3Sav2+gao468gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}