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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bee0c956d1135fba16a23cc604886b9a5d1d132d2c7bd80ec943e61c78b78a0' 
  AND token = 'vzagY9OTNJEu0oCgblM5ChKERbHy9YCOjY72MczLQeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}