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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad37267c1dfb6a2a0b40e42587b58e9915cb6e6f3399cf1d013f3fc26e50eea' 
  AND token = 'RQTReE/TPGlDgHnTvnKD96levcbvOM6nzqlYoDanXqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}