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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40448d74f003be681974dc2635e84a20d2547157fd20d57bf667073e7660abe1' 
  AND token = '2NeL25o9zZ4Okxk0KNg/Ie+ZJFwZ90+mka3VdpMa8YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}