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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01325d3a490daa245a07f402853d711387aea6ad1531acb8ee3e09d0986d21b0' 
  AND token = 'Fc2Q1cYWpS+zzeWNtXJ9YTMcs6gLZtEbFdUc1Z59ctw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}